How to Enhance Your Immune System | Dr. Roger Seheult

In this Huberman Lab Essentials episode, I explain how two key hormones control metabolism and discuss tools to enhance their levels to improve metabolic health. I discuss the pathways through which the brain and body interact to produce thyroid hormone and growth hormone, and how these hormones influence essential processes like tissue growth and repair, body composition, and energy production. I explain how thyroid hormone levels are influenced by key nutrients, such as iodine, selenium, and L-tyrosine. I also explain how practices such as exercise, sleep, meditation and sauna can offset age-related declines in growth hormone, to optimize overall hormone health and metabolism. Huberman Lab Essentials are short episodes (approximately 30 minutes) focused on essential science and protocol takeaways from past Huberman Lab episodes. Essentials will be released every Thursday, and our full-length episodes will still be released every Monday. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman David: https://davidprotein.com/huberman Timestamps 00:00:00 Huberman Lab Essentials; Hormones & Metabolism 00:01:41 Hypothalamus, Pituitary, Thyroid 00:03:22 Thyroid Hormone Functions, Tools: Iodine, Selenium, L-Tyrosine 00:07:55 Sponsor: Eight Sleep 00:09:27 Thyroid Hormone, Glucose & Metabolism; Thyroid Hormone Disorders 00:11:45 Growth Hormone Functions, Prescription Growth Hormone 00:14:41 Growth Hormone Release, Tools: Sleep & Bedtime Fasting 00:16:07 Growth Hormone Release, Tool: Meditation 00:18:21 Sponsor: AG1 00:19:24 Growth Hormone Release, Tools: Exercise, Warm-Up, Glucose, Cool Down 00:22:04 Growth Hormone Supplements, Arginine 00:24:07 Offsetting Age-Related Growth Hormone Decline 00:25:05 Temperature & Growth Hormone, Tool: Sauna Protocol 00:29:23 Sponsor: David Protein 00:30:38 Peptides, Sermorelin, Secretagogues, Risk 00:33:26 Recap & Key Takeaways Disclaimer & Disclosures

My guest is Dr. Richard Schwartz, Ph.D., therapist, author, and founder of Internal Family Systems (IFS) therapy. We discuss how IFS views the mind as a collection of parts, each shaped by different life experiences—both good and bad, including trauma. To demonstrate how IFS works, Dr. Schwartz guides Dr. Huberman and you, the listener, through an example IFS session. We also explore how IFS and body awareness can help break harmful thought and behavior patterns, promote emotional healing, and build healthier relationships. Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman David Protein: https://davidprotein.com/huberman Wealthfront**: https://wealthfront.com/huberman Function: https://functionhealth.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00:00 Dr. Richard Schwartz 00:02:11 Internal Family Systems (IFS), Self & Parts 00:07:23 Sponsors: BetterHelp & David Protein 00:09:44 Trauma & Parts: Exiles, Roles, Critic, Managers, Firefighters 00:15:32 Frustration & Anger, Surrender & Perspective 00:19:35 Feelings, Curiosity & Self-Exploration, Protecting Other Parts 00:29:35 Exploration of Inner Frustration, Judgement, Firefighters, Protectors 00:40:04 Titanium Teddy Bear, The Self & Curiosity, Tool: The 8 C’s & Self 00:46:41 Sponsors: AG1 & Wealthfront 00:49:24 IFS Therapy, Self-Exploration 00:53:47 Role Confusion, Conflict, Self & Clarity; Legacy Burdens 01:00:26 Cognitive vs Somatic Feelings; Tools: Localize Body Feeling, Curiosity 01:04:11 IFS & Psychedelics, Ketamine, Big Self, Journal Retractions 01:11:18 Early Morning, Breathwork, Exiles & Healing 01:13:53 Sponsor: Function 01:15:41 Shame, Racism, Protectors & Carrying Burden, Compassion 01:21:29 Unhealthy Romantic Relationships, Child-Parent Relationship 01:27:06 Therapist, Self-Exploration, Protectors & Introduction to Self 01:31:08 Tool: Questions for a Self-Exploration of Internal Protectors 01:39:30 Writing, Forming New Relationships with Parts, Leading with Self 01:42:51 Protectors, Managers, Firefighters, Suicidal & Addiction Behaviors 01:48:37 Overworking, Fear, Mortality 01:54:35 Technology & Distraction, Exiles, Worthlessness 01:58:58 Psychiatry, Medicine, New Ideas 02:02:58 Culture & Expanding Problems, Activism & Self 02:10:39 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures

In this Huberman Lab Essentials episode, I explain how hormones regulate hunger, appetite and feelings of satiety (fullness), along with strategies to help control appetite. I describe how the body senses nutrient levels and how the brain processes these signals to stimulate hunger or suppress appetite. I also discuss how certain foods can help curb hunger, while processed foods and emulsifiers can interfere with satiety signals, leading to overeating. Additionally, I cover how lifestyle factors such as exercise and meal timing regulate blood glucose levels, which in turn impact hunger and appetite. Huberman Lab Essentials episodes are approximately 30 minutes long and focus on essential science and protocol takeaways from past Huberman Lab episodes. Essentials will be released every Thursday, while our full-length episodes will continue to be released every Monday. This Huberman Lab Essentials is from the full-length Huberman Lab episode, “How Our Hormones Control Our Hunger, Eating & Satiety.” Read the full episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David Protein: https://davidprotein.com/huberman Mateina: https://drinkmateina.com/huberman LMNT: https://drinklmnt.com/huberman For all Huberman Lab sponsors, visit hubermanlab.com/sponsors. Timestamps 00:00:00 Huberman Lab Essentials; Hunger & Appetite 00:00:56 Hunger, Hypothalamus, Cortex & Mouth 00:04:46 Sponsor: David Protein 00:06:02 Melanocyte-Stimulating Hormone, AgRP Neurons, Ghrelin, Tool: Regular Meal Timing 00:10:13 Cholecystokinin (CCK), Tool: Omega-3s, Amino Acids & Blunting Appetite 00:13:26 Sponsor: AG1 00:14:30 Highly-Processed Foods, Emulsifiers, Tool: Whole Foods & Satiety Signals 00:19:10 Insulin, Glucose, Type 1 & 2 Diabetes 00:22:16 Sponsor: Mateina 00:23:41 Insulin & Glucagon, Tools: Food Order, Movement & Blood Glucose 00:27:26 Tool: Exercise & Stable Blood Sugar 00:29:38 Metformin, Ketogenic Diet, Blood Glucose 00:31:59 Sponsor: LMNT 00:33:16 Diabetes, Urine & Blood Sugar 00:35:40 Caffeine, Tool: Yerba Mate, Glucagon-Like Peptide -1 (GLP-1), Appetite 00:38:49 Recap & Key Takeaways Disclaimer & Disclosures

In this Huberman Lab Essentials episode, I explain how to optimize hormones—particularly testosterone, estrogen, and related sex steroids—to enhance fertility and overall well-being. I discuss the sources of testosterone and estrogen and how their levels fluctuate with age in both males and females. I also cover how behaviors such as exercise, cold and heat exposure, light exposure, illness, and breathing patterns affect hormones. Additionally, I examine specific supplements and replacement therapies, highlighting important precautions to consider when adjusting hormone levels. Huberman Lab Essentials episodes are approximately 30 minutes long and focus on key scientific insights and protocol takeaways from past Huberman Lab episodes. These short episodes will be released every Thursday, while our full-length episodes will continue to be released every Monday. Read the show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Huberman Lab Essentials; Hormones 00:01:15 Testosterone & Estrogen Sources & Age, Adrenals 00:03:34 Sponsor: Eight Sleep 00:05:05 Competition, Males & Testosterone; Dopamine 00:09:27 Testosterone Decreases, Expectant Fathers, Illness 00:11:30 Sleep Apnea, Testosterone, Estrogen, Cortisol, Tool: Nasal Breathing 00:15:57 Sponsor: AG1 00:17:00 Dopamine, Cortisol, Fertility, Tool: Light Viewing Behavior  00:19:31 Heat, Cold & Hormone Levels 00:21:14 Resistance & Endurance Training, Testosterone, Tool: Exercise Order 00:23:26 Estrogen, Menopause, Hormone Therapy 00:25:07 Sponsor: Function 00:26:54 Vitamins, Opioids, Supplements, Tongkat Ali, Cancer Risk 00:31:26 Luteinizing Hormone, hCG, Fadogia Agrestis, Tool: Blood Tests 00:36:00 Recap & Key Takeaways Disclaimer & Disclosures

My guest is Dr. Michael Platt, Ph.D., a professor of neuroscience and psychology at the University of Pennsylvania. We discuss how factors such as hormonal or social status influence what we value, how we make decisions, and even our perceptions across a range of areas, from who and what we find attractive to our political affiliations. We also discuss how humans evaluate and shift power in relationships and form hierarchies in groups. Dr. Platt also shares new science-based tools for improving focus, creativity, and attention. Read the full show notes for this episode at hubermanlab.com. Sponsors AG1: https://drinkag1.com/huberman Our Place: https://fromourplace.com/huberman Wealthfront**: https://wealthfront.com/huberman BetterHelp: https://betterhelp.com/huberman Function: https://functionhealth.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00:00 Dr. Michael Platt 00:02:12 Humans, Old World Primates & Decision-Making; Swiss Army Knife Analogy 00:07:52 Sponsors: Our Place & Wealthfront 00:11:01 Attention Allocation, Resource Foraging 00:16:40 Social Media; Marginal Value Theorem, Distraction 00:22:22 Tool: Remove Phone from Room; Attention & Urgency 00:25:23 Tool: Self Conversation; Visual Input, Attention as a Skill 00:29:29 Warming-Up Focus, Tool: Visual Aperture & Attention 00:38:57 Sponsor: AG1 00:40:13 Control of Attention, Tool: Changing Environment 00:44:07 Attention Continuum, Professions, Measuring Business Skill with Neuroscience 00:53:06 Theory of Mind, Covert Attention, Attentional Spotlights 01:00:05 Primates, Hormone Status, Brain Size, Monogamy 01:09:31 Monkeys, Neuronal Multiplexing & Context; Equitable Relationships 01:20:05 Sponsor: BetterHelp 01:21:11 Relationships, Power Dynamics, Neuroethology 01:29:34 Humans, Females & Hormone Status; Monkeys, Social Images, Hormones 01:38:03 Humans, Attractiveness, Value-Based Decision Making 01:44:32 Altruism, Group Selection & Cooperation, Selflessness 01:49:08 Males, Testosterone, Behavior Changes 01:55:46 Sponsor: Function 01:57:34 Oxytocin, Pro-Social Behaviors, Behavioral Synchrony 02:08:13 MDMA, Oxytocin, Anxiety; Social Touch, Despair & Isolation 02:17:12 Isolation, Social Connections & Strangers, Tool: Deep Conversation Questions 02:21:17 Bridging the Divide, Tribes & Superficial Biases 02:26:58 Testosterone, Risk-Taking Behavior 02:30:52 Decision-Making, Tool: Accurate or Fast? 02:38:31 Decision-Making, Impact of Time & Fatigue 02:45:23 Advertising, Status, Celebrity, Monkeys 02:52:19 Hierarchy; Abundance & Scarcity, Money & Happiness, Loss Aversion 03:02:47 Meme Coins, Celebrity Endorsement, Social Sensitivity 03:12:22 Decisions & Urgency; Bounded & Ecological Rationality 03:18:09 Longevity Movement; Mortality & Motivation 03:24:48 Retirement?, Serial Pursuits & Pivoting 03:30:17 Apple or Samsung?, Brand Loyalty, Empathy 03:38:15 Political Affiliation, Empathy 03:46:22 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures