EXTRA: The Opioid Tragedy — How We Got Here
3 June 2024 - 41 minsAn update of our 2020 series, in which we spoke with physicians, researchers, and addicts about the root causes of the crisis — and the tension between abstinence and harm reduction.
SOURCES:Gail D’Onofrio, professor and chair of emergency medicine at the Yale School of Medicine and chief of emergency services at Yale-New Haven Health.Keith Humphreys, professor of psychiatry and behavioral sciences at Stanford University.Stephen Loyd, chief medical officer of Cedar Recovery and chair of the Tennessee Opioid Abatement Council.Nicole O’Donnell, certified recovery specialist at the University of Pennsylvania's Center for Addiction Medicine and Policy.Jeanmarie Perrone, professor of emergenc...
666. This Is How Progress Happens
Economists don’t usually talk about “culture.” But Joel Mokyr argues that it’s the engine of innovation — and the Nobel Prize committee agreed. Stephen Dubner sits down for a thousand-year conversation (including advice!) with the new Nobel laureate.
53 mins
6 March Finished
The Most Powerful People You’ve Never Heard Of (Update)
Just beneath the surface of the global economy, there is a hidden layer of dealmakers for whom war, chaos, and sanctions can be a great business opportunity. In this updated episode from 2025, journalists Javier Blas and Jack Farchy help us shine a light on the shadowy realm of commodity traders.
1 hour 6 mins
4 March Finished
665. Werner Herzog Isn’t Afraid ...
... of bad reviews, meager financing, or artificial intelligence. But he is worried that the world is full of sloppy thinkers who mistake facts for the truth.
49 mins
27 February Finished
664. Are Thousands of Medical Cures Hiding in Plain Sight?
Existing drugs can sometimes be repurposed to treat rare diseases. But making that match can be hard — and the financial incentives are weak. Guest host Steve Levitt tries to solve the puzzle.
51 mins
20 February Finished
All You Need Is Nudge (Update)
When Richard Thaler first published Nudge, the world was just starting to believe in his brand of behavioral economics. In this 2021 episode, we ask: How has nudge theory held up in the face of a global financial meltdown, a pandemic, and other existential crises?
57 mins
18 February Finished
663. Is Weed a Performance-Enhancing Drug?
The science says no, at least not in the athletic sense. But the psychic benefits can be large — just ask former N.F.L. star Ricky Williams. He says athletes should consider cannabis a healing drug, not a party drug. Even the N.F.L. is starting to agree. (Part two of a two-part series.)
50 mins
13 February Finished